BDBM50155723 1-(6,7-Dimethoxy-1-phenethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone::CHEMBL187593

SMILES COc1cc2CCN(C(CCc3ccccc3)c2cc1OC)C(C)=O

InChI Key InChIKey=KZMBWEHNBRZOCJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50155723   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50155723(1-(6,7-Dimethoxy-1-phenethyl-3,4-dihydro-1H-isoqui...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at MT1 receptor (unknown origin) assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155723(1-(6,7-Dimethoxy-1-phenethyl-3,4-dihydro-1H-isoqui...)
Affinity DataIC50:  76nMAssay Description:Inhibitory concentration against Melatonin receptor type 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50155723(1-(6,7-Dimethoxy-1-phenethyl-3,4-dihydro-1H-isoqui...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against Melatonin receptor type 1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155723(1-(6,7-Dimethoxy-1-phenethyl-3,4-dihydro-1H-isoqui...)
Affinity DataIC50:  76nMAssay Description:Antagonist activity at MT2 receptor (unknown origin) assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed