BDBM50156085 6-Cyclohexylamino-9-{2-[(2-methoxy-ethyl)-methyl-amino]-ethyl}-9H-purine-2-carbonitrile::CHEMBL186062

SMILES COCCN(C)CCn1cnc2c(NC3CCCCC3)nc(nc12)C#N

InChI Key InChIKey=DEUHRFYIQWZXMJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156085   

TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156085(6-Cyclohexylamino-9-{2-[(2-methoxy-ethyl)-methyl-a...)
Affinity DataIC50:  76nMAssay Description:Inhibitory concentration against recombinant human cathepsin L by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156085(6-Cyclohexylamino-9-{2-[(2-methoxy-ethyl)-methyl-a...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against recombinant human cathepsin S by using Z-Leu-Leu-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156085(6-Cyclohexylamino-9-{2-[(2-methoxy-ethyl)-methyl-a...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against recombinant human cathepsin K by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed