BDBM50157359 4-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluoromethyl-phenyl]-6-[3-(2H-tetrazol-5-yl)-piperidin-1-yl]-pyrimidine::CHEMBL180412

SMILES CC(C)c1ccccc1Sc1ccc(cc1C(F)(F)F)-c1cc(ncn1)N1CCCC(C1)c1nnn[nH]1

InChI Key InChIKey=JLATZOOYNDMRMO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157359   

TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157359(4-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluoromethy...)
Affinity DataEC50:  20nMAssay Description:Effective concentration to measure the adherence of LFA-1 expressing JY8 cells to immobilized ICAM-1 in cell-based adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157359(4-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluoromethy...)
Affinity DataIC50:  51nMAssay Description:Inhibitory concentration against integrin LFA-1/ICAM-1 binding complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed