BDBM50158012 CHEMBL183351::N-[13-(5-Chloro-thiophene-2-sulfonylamino)-tricyclo[8.2.1.0*3,8*]trideca-3(8),4,6-trien-5-yl]-2-(4-phenyl-piperazin-1-yl)-acetamide

SMILES Clc1ccc(s1)S(=O)(=O)NC1C2CCC1Cc1cc(NC(=O)CN3CCN(CC3)c3ccccc3)ccc1C2

InChI Key InChIKey=PFTCBIBMHGBWSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158012   

LigandPNGBDBM50158012(CHEMBL183351 | N-[13-(5-Chloro-thiophene-2-sulfony...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed