BDBM50158054 4-[7-(1,2,3,6-Tetrahydro-pyridin-4-yl)-[1,3]dioxolo[4,5-f]indole-5-sulfonyl]-phenylamine::CHEMBL361180

SMILES Nc1ccc(cc1)S(=O)(=O)n1cc(C2=CCNCC2)c2cc3OCOc3cc12

InChI Key InChIKey=RIPUIEGVRLGBBX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158054   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158054(4-[7-(1,2,3,6-Tetrahydro-pyridin-4-yl)-[1,3]dioxol...)
Affinity DataKi:  1nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158054(4-[7-(1,2,3,6-Tetrahydro-pyridin-4-yl)-[1,3]dioxol...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed