BDBM50160616 CHEMBL3786240

SMILES Brc1cccc2cc(cn12)C(=O)N[C@H]1CN2CCC1CC2

InChI Key InChIKey=GHHHWOPNWZYRLT-AWEZNQCLSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160616   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50160616(CHEMBL3786240)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50160616(CHEMBL3786240)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in xenopus oocytes in presence of alpha7 nAChR positive allosteric modulator PNU-120596More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50160616(CHEMBL3786240)
Affinity DataEC50:  1.78E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in xenopus oocytes preincubated for 10 mins followed by acetylcholine addition by patch clamp electr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed