BDBM50162737 4-Benzyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL180333

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(Cc2ccccc2)CC1C(=O)NO

InChI Key InChIKey=BLVHWPCGFOTRGU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162737   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162737(4-Benzyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  61nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162737(4-Benzyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  212nMAssay Description:Inhibitory concentration against matrix metalloproteinase-1 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162737(4-Benzyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  52nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed