BDBM50162843 3-(1-{2-Hydroxy-3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperidin-4-yl)-1,5-dimethyl-1,3-dihydro-benzoimidazol-2-one::CHEMBL360969

SMILES Cc1ccc2n(C)c(=O)n(C3CCN(CC(O)Cn4nc(c5CN(CCc45)S(C)(=O)=O)-c4ccc(cc4)C(F)(F)F)CC3)c2c1

InChI Key InChIKey=UGLKTMABKZLPJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162843   

TargetCathepsin S(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162843(3-(1-{2-Hydroxy-3-[5-methanesulfonyl-3-(4-trifluor...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed