BDBM50163859 CHEMBL3797835::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 12
SMILES CCCSc1c(F)c(F)c(c(NC2CCCCCCC2)c1F)S(N)(=O)=O
InChI Key InChIKey=KXHWJJLARFHTQI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 50163859
Affinity DataKoff: 3.30E+5s-1pH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 8 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 390nMpH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 8 by surface pl...More data for this Ligand-Target Pair
Affinity DataKoff: 2.90E+5s-1Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 1.30E+5s-1Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 5.80E+4s-1pH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 1.60E+5s-1pH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 7 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 19nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface pl...More data for this Ligand-Target Pair
Affinity DataKon: 0.0500M-1s-1Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 510nMAssay Description:Binding affinity to human recombinant CA7 after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Binding affinity to human recombinant CA13 by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.00790M-1s-1pH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 140nMpH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 6 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMpH: 6.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 6 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 840nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 7 by surface pl...More data for this Ligand-Target Pair
Affinity DataKon: 0.00720M-1s-1pH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 7 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 46nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 7 by surface pl...More data for this Ligand-Target Pair
Affinity DataKon: 0.00620M-1s-1pH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 8 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 9.10E+3nMAssay Description:Binding affinity to human recombinant CA1 expressed in Escherichia coli by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 74nMAssay Description:Binding affinity to human recombinant CA7 by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.00770M-1s-1Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 450nMAssay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 27nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.170nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0100M-1s-1Assay Description:Binding affinity to human recombinant CA7 assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 2.00E+4s-1Assay Description:Binding affinity to human recombinant CA7 assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair