BDBM50164541 (2R,3S)-1-Phenanthren-2-ylmethyl-piperazine-2,3-dicarboxylic acid::CHEMBL192957

SMILES OC(=O)[C@H]1NCCN(Cc2ccc3c(ccc4ccccc34)c2)[C@H]1C(O)=O

InChI Key InChIKey=HMWHYVPVLJQNRD-RBUKOAKNSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50164541   

TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164541((2R,3S)-1-Phenanthren-2-ylmethyl-piperazine-2,3-di...)
Affinity DataKi:  2.67E+3nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
University Walk

Curated by ChEMBL
LigandPNGBDBM50164541((2R,3S)-1-Phenanthren-2-ylmethyl-piperazine-2,3-di...)
Affinity DataKi:  2.70E+3nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Walk

Curated by ChEMBL
LigandPNGBDBM50164541((2R,3S)-1-Phenanthren-2-ylmethyl-piperazine-2,3-di...)
Affinity DataKi:  1.03E+4nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2B expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
University Walk

Curated by ChEMBL
LigandPNGBDBM50164541((2R,3S)-1-Phenanthren-2-ylmethyl-piperazine-2,3-di...)
Affinity DataKi:  1.03E+4nMAssay Description:Antagonist activity rat recombinant GluN1/GluN2B receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University Walk

Curated by ChEMBL
LigandPNGBDBM50164541((2R,3S)-1-Phenanthren-2-ylmethyl-piperazine-2,3-di...)
Affinity DataKi:  1.12E+4nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University Walk

Curated by ChEMBL
LigandPNGBDBM50164541((2R,3S)-1-Phenanthren-2-ylmethyl-piperazine-2,3-di...)
Affinity DataKi:  1.12E+4nMAssay Description:Antagonist activity at rat recombinant GluN1/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed