BDBM50165418 8-{2-[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL446180

SMILES Fc1ccc(N2CCN(CCN3C(=O)CC4(CCCC4)CC3=O)CC2)c(F)c1

InChI Key InChIKey=NQYDFNJSOIGZSU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50165418   

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50165418(8-{2-[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-ethy...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity for human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50165418(8-{2-[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-ethy...)
Affinity DataKi:  24nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50165418(8-{2-[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-ethy...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50165418(8-{2-[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-ethy...)
Affinity DataKi:  3.80E+3nMAssay Description:Binding affinity for human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed