BDBM50167084 CHEMBL3798524

SMILES Oc1cn(ccc1=O)-c1cc(ccn1)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=GWOKGPRSSNNVTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167084   

TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50167084(CHEMBL3798524)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50167084(CHEMBL3798524)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed