BDBM50167696 (1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydroxy-1,4a-dimethylphenanthrene-1-carboxylic acid::(1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid::12-hydroxypodocarpa-8,11,13-trien-16-oic acid::CHEMBL421115::Podocarpic acid

SMILES C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(O)=O

InChI Key InChIKey=VJILEYKNALCDDV-OIISXLGYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50167696   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167696((1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydr...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human recombinant LXRbeta expressed in Escherichia coli BL21 cells assessed as association of recombinant SRC1 to LXRbeta ligand ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167696((1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167696((1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-alpha in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167696((1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydr...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration for cofactor association with recombinant liver X receptor-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167696((1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydr...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human recombinant LXRalpha expressed in Escherichia coli BL21 cells assessed as association of recombinant SRC1 to LXRalpha ligan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167696((1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydr...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration for cofactor association with recombinant liver X receptor-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed