BDBM50168045 3-(4-Fluoro-3-methyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL192035
SMILES COC(=O)C1C2CCC(CC1c1ccc(F)c(C)c1)N2C
InChI Key InChIKey=JWQGRCSMNJKNOQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50168045
Affinity DataKi: 74nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 258nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 13.7nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of [3H]nisoxetine binding to rat cerebral cortex norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of [3H]paroxetine binding to rat cortex serotonin transporter More data for this Ligand-Target Pair