BDBM50170175 CHEMBL178084::cis-N*2*-[4-(4-Bromo-2-trifluoromethoxy-benzylamino)-cyclohexyl]-N*4*,N*4*-dimethyl-quinazoline-2,4-diamine

SMILES CN(C)c1nc(NC2CCC(CC2)NCc2ccc(Br)cc2OC(F)(F)F)nc2ccccc12

InChI Key InChIKey=PUTAQVRRQAPAQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170175   

TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50170175(CHEMBL178084 | cis-N*2*-[4-(4-Bromo-2-trifluoromet...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50170175(CHEMBL178084 | cis-N*2*-[4-(4-Bromo-2-trifluoromet...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50170175(CHEMBL178084 | cis-N*2*-[4-(4-Bromo-2-trifluoromet...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]PYY as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed