BDBM50171134 CHEMBL370347::Isoquinoline-1-carboxylic acid {(S)-5-benzoyl-1-[((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-methyl]-2-oxo-[1,5]diazocan-3-yl}-amide

SMILES OC1OC(=O)C[C@@H]1NC(=O)CN1CCCN(C[C@H](NC(=O)c2nccc3ccccc23)C1=O)C(=O)c1ccccc1

InChI Key InChIKey=IHIVFURWIXMBQM-SIPOYVIUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171134   

TargetCaspase-3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171134(CHEMBL370347 | Isoquinoline-1-carboxylic acid {(S)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of caspase 3 using fluorogenic substrate and BMG Fluostar plate reader for 30 min at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171134(CHEMBL370347 | Isoquinoline-1-carboxylic acid {(S)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of caspase 8 using fluorogenic substrate and BMG Fluostar plate reader for 30 min at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171134(CHEMBL370347 | Isoquinoline-1-carboxylic acid {(S)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of caspase-1 using fluorogenic substrate and BMG Fluostar plate reader for 30 min at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed