BDBM50171215 CHEMBL198302::Cyclic sulfamide
SMILES FC(F)(F)CN1C[C@@]2(NS1(=O)=O)[C@H]1CC[C@@H]2Cc2cc(\C=C\CN3CCOCC3)ccc2C1
InChI Key InChIKey=ADXBEEAHQAXNTH-IHITYGOKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50171215
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibitory concentration against gamma-secretase in whole cell SH-SY5Y assayMore data for this Ligand-Target Pair