BDBM50171217 CHEMBL194084::Cyclic sulfamide

SMILES CC1CCN(C\C=C\c2ccc3C[C@@H]4CC[C@H](Cc3c2)[C@@]42CN(CC(F)(F)F)S(=O)(=O)N2)CC1

InChI Key InChIKey=FSQUYIAMRHDXDD-HONITSIMSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171217   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL

LigandBDBM50171217(CHEMBL194084 | Cyclic sulfamide)Copy SMILESCopy InChI

Affinity DataIC50:  18nMAssay Description:Inhibitory concentration against gamma-secretase in whole cell SH-SY5Y assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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