BDBM50171916 CHEMBL3805299::US10106508, Compound I-11
SMILES COCCOc1cc2ncnc(Nc3ccc(C)c(c3)[N+]([O-])=O)c2c2OCCOc12
InChI Key InChIKey=FSRMUDDPGLEQSI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50171916
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair