BDBM50172078 LY-2801653::Merestinib
SMILES Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1
InChI Key InChIKey=QHADVLVFMKEIIP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50172078
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human full length AXL after 4 hrs followed by stimulation with human recombinant Gas6 for 15 minutes by cell based assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human full length AXL by scintillation counting method in presence of 33P-gammaATPMore data for this Ligand-Target Pair