BDBM50173461 4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylamino)-6-chloro-chromen-2-one::CHEMBL194564

SMILES Clc1ccc2oc(=O)cc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1

InChI Key InChIKey=FBKMRPXQTLKWBJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173461   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173461(4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  28nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173461(4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of human potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173461(4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed