BDBM50173944 5'-phenyl-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine]::CHEMBL195345

SMILES C1c2cc(cnc2O[C@]11CN2CCC1CC2)-c1ccccc1

InChI Key InChIKey=GIRLVGYIIVFTLI-IBGZPJMESA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50173944   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50173944(5'-phenyl-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50173944(5'-phenyl-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,...)
Affinity DataKi:  2nMAssay Description:Binding affinity to 5-HT3A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50173944(5'-phenyl-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173944(5'-phenyl-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,...)
Affinity DataKi:  73nMAssay Description:Binding affinity for human 5-hydroxytryptamine 3 serotonin membrane receptor using [3H]GR-65630More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed