BDBM501745 N-Cyclopentyl-3-(5-((7-methyl-9-oxo-5-(2-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)ethoxy)-9H-xanthen-3-yl)oxy)pyridin-2-yl)propanamide::US11028064, Example 59

SMILES Cc1cc(OCCN2CCN(CC(F)(F)F)CC2)c2oc3cc(Oc4ccc(CCC(=O)NC5CCCC5)nc4)ccc3c(=O)c2c1

InChI Key InChIKey=HNFWLNRGNLBPCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501745   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501745(N-Cyclopentyl-3-(5-((7-methyl-9-oxo-5-(2-(4-(2,2,2...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Auckland Uniservices

US Patent
LigandPNGBDBM501745(N-Cyclopentyl-3-(5-((7-methyl-9-oxo-5-(2-(4-(2,2,2...)
Affinity DataIC50: <100nMAssay Description:IC50 values were determined using the Z′-LYTEŽ activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent