BDBM50174901 5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-yl)-1H-indazol-3-amine::CHEMBL380782

SMILES Clc1ccc2[nH]nc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1

InChI Key InChIKey=AHDSVCDBYISCAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174901   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174901(5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174901(5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  1.82E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed