BDBM50174905 5-chloro-N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)piperidin-4-yl)-1H-indazol-3-amine::CHEMBL198588

SMILES Clc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCCOc5c4)CC3)c2c1

InChI Key InChIKey=BCPYDPOPHGIAPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174905   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174905(5-chloro-N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-y...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174905(5-chloro-N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-y...)
Affinity DataIC50:  1.89E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed