BDBM50177642 (R)-8-chloro-11-(1-methanesulfonyl-piperidin-4-yl)-5-piperazin-1-yl-11H-benzo[5,6]cyclohepta[1,2-b]pyridine::CHEMBL382828

SMILES CS(=O)(=O)N1CCC(CC1)[C@@H]1c2ccc(Cl)cc2C=C(N2CCNCC2)c2cccnc12

InChI Key InChIKey=ZIGSEKZLCYCKCR-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177642   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177642((R)-8-chloro-11-(1-methanesulfonyl-piperidin-4-yl)...)
Affinity DataIC50:  76nMAssay Description:Inhibition of farnesyltransferase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed