BDBM50179131 (2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino)-3-methylhexa-2,4-dienoic acid::CHEMBL427391

SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C

InChI Key InChIKey=PQUKTZDZZRYNRP-XYJQQDCNSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50179131   

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179131((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Affinity DataKi:  42nMAssay Description:Binding affinity to RXRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179131((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Affinity DataKi:  99nMAssay Description:Binding affinity to RXRgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179131((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Affinity DataKi:  152nMAssay Description:Binding affinity to RXRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179131((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Affinity DataEC50:  117nMAssay Description:Transactivation of RXRbeta in CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179131((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Affinity DataEC50:  64nMAssay Description:Transactivation of RXRalpha in CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179131((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...)
Affinity DataEC50:  125nMAssay Description:Transactivation of RXRgamma in CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed