BDBM50179135 (R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-cyclohexyl-4-(5,5-dimethyl-1,1-dioxo-1lambda*6*-isothiazolidin-2-ylmethyl)-piperidin-1-yl]-2-oxo-ethyl}-amide::CHEMBL383719
SMILES CC1(C)CCN(CC2(CCN(CC2)C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H]2Cc3ccccc3CN2)C2CCCCC2)S1(=O)=O
InChI Key InChIKey=UHMCIGUGJPINOI-ROJLCIKYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50179135
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1BR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 450nMAssay Description:Activity against human MC3R by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 5.80nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 460nMAssay Description:Activity against human MC1BR by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 850nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair