BDBM50179245 2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1H-indol-6-yloxy]propoxy}indol-1-yl)ethanoic acid::CHEMBL371091

SMILES CCCc1c(OCCCOc2ccc3n(CC(O)=O)ccc3c2)ccc2c(c[nH]c12)C(=O)C(F)(F)F

InChI Key InChIKey=GHGWDIVXERLYFN-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50179245   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179245(2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1...)
Affinity DataEC50:  9.17E+3nMAssay Description:Functional activity at human PPAR delta in Huh7 cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179245(2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Functional activity at human PPAR gamma in Huh7 cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179245(2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1...)
Affinity DataEC50:  2.20E+3nMAssay Description:Functional activity at human PPAR alpha in Huh7 cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179245(2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1...)
Affinity DataIC50:  2.41E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed