BDBM50181838 4-amino-5-chloro-2-ethoxy-N-[(1S,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl]benzamide::CHEMBL201019

SMILES CCOc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CCN2CCC[C@@H]12

InChI Key InChIKey=QDTWANUYGDJQMC-NHYWBVRUSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181838   

Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181838(4-amino-5-chloro-2-ethoxy-N-[(1S,7aS)-hexahydro-1H...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]GR65630 from 5HT3 receptor in brain cortex from Wistar ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181838(4-amino-5-chloro-2-ethoxy-N-[(1S,7aS)-hexahydro-1H...)
Affinity DataIC50:  5.30E+3nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181838(4-amino-5-chloro-2-ethoxy-N-[(1S,7aS)-hexahydro-1H...)
Affinity DataEC50:  195nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed