BDBM50182280 CHEMBL3819245

SMILES Oc1ccccc1C(=O)\C=C\N1CCc2c(C1)ncnc2NC1CC1

InChI Key InChIKey=IABGSEADKPXCRQ-CSKARUKUSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182280   

TargetProtein polybromo-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182280(CHEMBL3819245)
Affinity DataKd:  152nMAssay Description:Binding affinity to human PB1 isoform 2 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration CalorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription activator BRG1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182280(CHEMBL3819245)
Affinity DataKd:  49nMAssay Description:Binding affinity to human SMARCA4 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein polybromo-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182280(CHEMBL3819245)
Affinity DataKd:  28nMAssay Description:Binding affinity to human PB1 isoform 5 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed