BDBM50182698 CHEMBL204085::N-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-5-(4-morpholinyl)-2-pentynamide
SMILES Fc1ccc(Nc2ncnc3ccc(NC(=O)C#CCCN4CCOCC4)cc23)cc1Cl
InChI Key InChIKey=OETCDAITXCDXIB-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50182698
Affinity DataIC50: 12nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair