BDBM50182946 4-((S)-2-amino-3-oxo-3-((S)-2-(4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propyl)-3,5-dimethylbenzamide::CHEMBL205049
SMILES Cc1cc(cc(C)c1C[C@H](N)C(=O)N1CCCC[C@H]1c1nc(c[nH]1)-c1ccccc1)C(N)=O
InChI Key InChIKey=ORFHSHFAWAJFLG-GMAHTHKFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50182946
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brainMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brainMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Activity against mu opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(MOUSE)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataEC50: 135nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataEC50: 135nMAssay Description:Agonist activity at delta opioid receptor expressed in CHO-hg cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair