BDBM50184434 2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine::CHEMBL382010
SMILES CN1CCc2ccccc2Cc2cc(O)ccc2CC1
InChI Key InChIKey=PWYCTCPWHXJEDU-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50184434
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 8.90nMAssay Description:Displacement of [3H]SCH 23390 from D1 dopamine receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of D2L dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 36.9nMAssay Description:Displacement of [3H]spiperone from D2L dopamine receptorMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 37.5nMAssay Description:Inhibition of D5 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 42.3nMAssay Description:Binding affinity to D5 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Friedrich-Schiller-UniversitäT Jena
Curated by ChEMBL
Affinity DataKi: 296nMAssay Description:Binding affinity to D3 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair