BDBM50184439 3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine::CHEMBL381936

SMILES CN1CCc2cc(O)ccc2Cc2ccc(O)cc2CC1

InChI Key InChIKey=SBKJMNCSBLEGCS-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50184439   

TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184439(3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibe...)
Affinity DataKi:  0.540nMAssay Description:Inhibition of D5 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184439(3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibe...)
Affinity DataKi:  1.68nMAssay Description:Binding affinity to D5 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184439(3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibe...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]SCH 23390 from D1 dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184439(3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibe...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184439(3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibe...)
Affinity DataKi:  19nMAssay Description:Inhibition of D2L dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184439(3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibe...)
Affinity DataKi:  58.7nMAssay Description:Displacement of [3H]spiperone from D2L dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184439(3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibe...)
Affinity DataKi:  342nMAssay Description:Binding affinity to D3 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed