BDBM50185332 3-(3,5-difluoropyridin-4-yl)-5-[4-fluoro-3-(3-fluoropyridin-2-yl)phenyl]pyridazine::CHEMBL207840

SMILES Fc1ccc(cc1-c1ncccc1F)-c1cnnc(c1)-c1c(F)cncc1F

InChI Key InChIKey=CVOASAXXOXOGQG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185332   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185332(3-(3,5-difluoropyridin-4-yl)-5-[4-fluoro-3-(3-fluo...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185332(3-(3,5-difluoropyridin-4-yl)-5-[4-fluoro-3-(3-fluo...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185332(3-(3,5-difluoropyridin-4-yl)-5-[4-fluoro-3-(3-fluo...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed