BDBM50185410 (4aS,6S,8aR)-6-(4-chloro-benzenesulfonyl)-6-(2,5-difluoro-phenyl)-3-ethyl-octahydro-benzo[c][1,2]thiazine 2,2-dioxide::CHEMBL377691

SMILES CCC1C[C@@H]2C[C@](CC[C@@H]2NS1(=O)=O)(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=PFBYQYZXEMYQMF-HMBBNITOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185410   

LigandPNGBDBM50185410((4aS,6S,8aR)-6-(4-chloro-benzenesulfonyl)-6-(2,5-d...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of gamma secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed