BDBM50186782 CHEMBL380275::N-(4-chloro-3-trifluoromethyl-phenyl)-3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperidin-4-yl]-propionamide

SMILES Fc1ccc(NC(=O)CCC2(CCN(CC2)C2CCCC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1Cl

InChI Key InChIKey=XIWVUFWFJPGJBC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186782   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186782(CHEMBL380275 | N-(4-chloro-3-trifluoromethyl-pheny...)
Affinity DataKi:  30nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186782(CHEMBL380275 | N-(4-chloro-3-trifluoromethyl-pheny...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed