BDBM50186813 3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopropylmethyl-piperidin-4-yl]-N-(3,4-difluoro-phenyl)-propionamide::CHEMBL212265

SMILES Fc1ccc(NC(=O)CCC2(CCN(CC3CC3)CC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1F

InChI Key InChIKey=ZUHRVSHVHCVCNK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186813   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186813(3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopropylmethyl-...)
Affinity DataKi:  8nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186813(3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopropylmethyl-...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed