BDBM50189368 CHEMBL214215::N'-(1-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)carbamoyl)cyclohexanecarbonyl)-3-methoxybenzohydrazide

SMILES COc1cccc(c1)C(=O)NNC(=O)C1(CCCCC1)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=WWJJTCYWVNPFIZ-MBIQTGHCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189368   

TargetCaspase-1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189368(CHEMBL214215 | N'-(1-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50:  240nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189368(CHEMBL214215 | N'-(1-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of caspase8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189368(CHEMBL214215 | N'-(1-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed