BDBM50189372 CHEMBL379764::N'-(1-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)carbamoyl)cyclopentanecarbonyl)-3-methoxybenzohydrazide

SMILES COc1cccc(c1)C(=O)NNC(=O)C1(CCCC1)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=QVKRFRPFNMDNDV-KNVGNIICSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189372   

TargetCaspase-1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189372(CHEMBL379764 | N'-(1-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50:  200nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189372(CHEMBL379764 | N'-(1-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189372(CHEMBL379764 | N'-(1-(((3S)-2-hydroxy-5-oxo-tetrah...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of caspase8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed