BDBM50189704 3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-5-isobutyryl-2-[4-(3-methyluriedo)phenyl]-4-oxothieno[2,3-b]pyridine::CHEMBL377396
SMILES CNC(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1
InChI Key InChIKey=YEVRFOQFAUPFAJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50189704
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing human LHRH receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptorMore data for this Ligand-Target Pair