BDBM50190458 CHEMBL386222::sulfuric acid mono-(4-{4-[N-(3,5-diamino-6-chloropyrazine-2-carbonyl)guanidine]butyl}phenyl)ester

SMILES NC(NC(=O)c1nc(Cl)c(N)nc1N)=NCCCCc1ccc(cc1)S(O)(=O)=O

InChI Key InChIKey=JVPNJNUDXQTRKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190458   

TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190458(CHEMBL386222 | sulfuric acid mono-(4-{4-[N-(3,5-di...)
Affinity DataIC50:  21nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed