BDBM50190594 23-N-(carbo-2'-adamantyloxy)-3alpha,7alpha-dihydroxy-24-nor-5beta-cholan-23-amine::CHEMBL3138089

SMILES [H][C@@]12CCC([C@H](C)CCNC(=O)OC3C4CC5CC(C4)CC3C5)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](O)CC2C[C@H](O)CC[C@]12C

InChI Key InChIKey=OFYUAEPVYQGEEI-JLIHUEMFSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190594   

TargetBile acid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50190594(23-N-(carbo-2'-adamantyloxy)-3alpha,7alpha-dihydro...)
Affinity DataEC50:  600nMAssay Description:Binding affinity to FXR assessed as ligand-dependent SRC1 recruitment by FRET based co-activator assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed