BDBM50190677 (R)-3'-(3-bromobenzo[b]thiophen-5-yl)spiro[1-azabicyclo[2.2.2]-octane-3,5'-oxazolidin]-2'-one::CHEMBL211575

SMILES Brc1coc2ccc(cc12)N1C[C@]2(CN3CCC2CC3)OC1=O

InChI Key InChIKey=BSLJTEKAJGEMHJ-KRWDZBQOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190677   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190677((R)-3'-(3-bromobenzo[b]thiophen-5-yl)spiro[1-azabi...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50190677((R)-3'-(3-bromobenzo[b]thiophen-5-yl)spiro[1-azabi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed