BDBM50190787 CHEMBL3965948
SMILES Clc1cc(Nc2ncnc3cc4oc(=O)n(CCOC(=O)CBr)c4cc23)ccc1N1CCOCC1
InChI Key InChIKey=HVDZCCXJWIROKH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50190787
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of His-tagged human HER2 (676 to 1255 residues) expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged wild type recombinant human EGFR (668 to 1210 residues) expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair