BDBM50190803 CHEMBL3982289
SMILES ClCC(=O)OCCn1c2cc3c(Nc4ccc(N5CCOCC5)c(Cl)c4)ncnc3cc2oc1=O
InChI Key InChIKey=PBSHQQJKKJPYHE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50190803
TargetEpidermal growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of GST-tagged wild type recombinant human EGFR (668 to 1210 residues) expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of His-tagged human HER2 (676 to 1255 residues) expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair