BDBM50190803 CHEMBL3982289

SMILES ClCC(=O)OCCn1c2cc3c(Nc4ccc(N5CCOCC5)c(Cl)c4)ncnc3cc2oc1=O

InChI Key InChIKey=PBSHQQJKKJPYHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190803   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190803(CHEMBL3982289)
Affinity DataIC50:  19nMAssay Description:Inhibition of GST-tagged wild type recombinant human EGFR (668 to 1210 residues) expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190803(CHEMBL3982289)
Affinity DataIC50:  35nMAssay Description:Inhibition of His-tagged human HER2 (676 to 1255 residues) expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed