BDBM50191401 (2'Z,3' E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrrolidin-1-ylethyl)oxime] hydrochloride::CHEMBL377981

SMILES Cn1c(O)c(C2=Nc3ccccc3\C2=N/OCC[NH+]2CCCC2)c2cccc(Br)c12

InChI Key InChIKey=LEBAXTFUELGCGQ-LHLOQNFPSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191401   

TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191401((2'Z,3' E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrr...)
Affinity DataIC50:  1.30E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191401((2'Z,3' E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed