BDBM50191498 CHEMBL3907533
SMILES CCOc1cc2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2cc1NC(=O)\C=C\CN1CCOCC1
InChI Key InChIKey=WPKVIBFJECQBCV-RMKNXTFCSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50191498
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Irreversible inhibition of GST-tagged ERBB2 (unknown origin) (Ile-675 to Val-1256 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Irreversible inhibition of GST-tagged ERBB1 (unknown origin) (Met-668 to Ala-1211 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Irreversible inhibition of human recombinant GST-tagged JAK3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in polyglutamic...More data for this Ligand-Target Pair