BDBM50191508 2-{4-[4'-chloro-4-(morpholine-4-carbonyl)biphenyl-2-ylmethoxy]-2-fluorophenyl}-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid::CHEMBL379435

SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cc(ccc2-c2ccc(Cl)cc2)C(=O)N2CCOCC2)cc1F

InChI Key InChIKey=MSIXHHQWTQNSCX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191508   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191508(2-{4-[4'-chloro-4-(morpholine-4-carbonyl)biphenyl-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1)TBA
LigandPNGBDBM50191508(2-{4-[4'-chloro-4-(morpholine-4-carbonyl)biphenyl-...)
Affinity DataIC50:  7.14E+7nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1)TBA
LigandPNGBDBM50191508(2-{4-[4'-chloro-4-(morpholine-4-carbonyl)biphenyl-...)
Affinity DataIC50:  7.14E+7nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article